About the Authors

Li Zhang

zhangl3@ccf.org

Affiliations Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America, Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio, United States of America, Department of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio, United States of America

Mohammed S. Orloff

Affiliations Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio, United States of America

Sean Reber

Affiliation Department of Computer Science, Kent State University, Kent, Ohio, United States of America

Shengchao Li

Affiliation Department of Biostatistics, Johns Hopkins School of Public Health, Baltimore, Maryland, United States of America

Ye Zhao

Affiliation Department of Computer Science, Kent State University, Kent, Ohio, United States of America

Charis Eng

Affiliations Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio, United States of America, Stanley Shalom Zielony Institute for Nursing Excellence, Cleveland Clinic, Cleveland, Ohio, United States of America, Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio, United States of America, CASE Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Participated in study design and interpreted the results: LZ. Participated in study design, coordinated the database and interpreted the results: SR. Developed the software: MO. Developed the software: SL. Developed the software: YZ. Participated in study design, interpreted the analysis and critically revised the manuscript: CE. Conceived and designed the experiments: LZ MO CE. Analyzed the data: LZ. Contributed reagents/materials/analysis tools: LZ MO SB SL YZ. Wrote the paper: LZ MO CE.