About the Authors

Hui Shen

Contributed equally to this work with: Hui Shen, Wei Zhang

Affiliation Department of Medicine and Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America

Wei Zhang

Contributed equally to this work with: Hui Shen, Wei Zhang

Affiliation Department of Medicine and Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America

Clara Abraham

Affiliation Department of Medicine, Yale University School of Medicine, New Haven, Connecticut, United States of America

Judy H. Cho

judy.cho@yale.edu.

Affiliation Department of Medicine and Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America

Competing Interests

JHC is a Pfizer consultant. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: HS WZ CA JHC. Performed the experiments: HS WZ. Analyzed the data: HS WZ JHC. Wrote the paper: HS WZ CA JHC.