About the Authors

Peter Jones

sejjprj@live.ucl.ac.uk

Affiliations Critical Care Group - Portex Unit, Institute of Child Health, University College London, London, Great Britain, Réanimation Pédiatrique, Assistance Publique-Hôpitaux de Paris, Hôpital Robert Debré, Paris, France

Mark J. Peters

Affiliation Critical Care Group - Portex Unit, Institute of Child Health, University College London, London, Great Britain

Nathalia Pinto da Costa

Affiliation Réanimation Pédiatrique, Assistance Publique-Hôpitaux de Paris, Hôpital Robert Debré, Paris, France

Tobias Kurth

Affiliations Institut National de la Sante et de la Recherche Medical, Bordeaux, France, Neuroepidemiology, University of Bordeaux, Bordeaux, France, Division of Preventive Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Corinne Alberti

Affiliations Unité d’Epidémiologie Clinique, Assistance Publique-Hôpitaux de Paris, Hôpital Robert Debré, Paris, France, Institut National de la Sante et de la Recherche Medical CIE 5, Hôpital Robert Debré, Paris, France, Université Paris Diderot, Paris, France

Katia Kessous

Affiliation Réanimation Pédiatrique, Assistance Publique-Hôpitaux de Paris, Hôpital Robert Debré, Paris, France

Noella Lode

Affiliation Réanimation Pédiatrique, Assistance Publique-Hôpitaux de Paris, Hôpital Robert Debré, Paris, France

Stephane Dauger

Affiliations Réanimation Pédiatrique, Assistance Publique-Hôpitaux de Paris, Hôpital Robert Debré, Paris, France, Université Paris Diderot, Paris, France

Competing Interests

The authors have the following interests. Tobias Kurth has received within the last 2 years investigator-initiated research funding from Merck. He is a consultant to World Health Information Science Consultants, LLC; he has received honoraria Merck for educational lectures and from MAP Pharmaceutical for contributing to a scientific advisory panel. The authors are grateful to Welch Allwyn for the generous donation of the ECG paper used by the ICT team. There are no patents, products in development or marketed products to declare. This does not alter the authors′ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: PJ SD CA KK NL NP. Performed the experiments: PJ KK NP SD. Analyzed the data: PJ MJP TK NP SD. Wrote the paper: PJ MJP SD TK.