About the Authors

Christina E. N. Lord

Affiliation Department of Biology, Dalhousie University, Halifax, Nova Scotia, Canada

Adrian N. Dauphinee

Affiliation Department of Biology, Dalhousie University, Halifax, Nova Scotia, Canada

Rebecca L. Watts

Affiliation Department of Biology, Dalhousie University, Halifax, Nova Scotia, Canada

Arunika H. L. A. N. Gunawardena

arunika.gunawardena@dal.ca

Affiliation Department of Biology, Dalhousie University, Halifax, Nova Scotia, Canada

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Carried out experiments including: original optimization, and all replicates of the Kinetics for YVADase activity (including all control and treated samples), the staining and quantification of the actin-cytoskeleton from the following treatments, all non-treated controls, caspase-inhibitor treated, as well as CsA treated samples: CENL. Jointly optimized the original application of latrunculin B and also jointly contributed to the staining and quantification of actin following treatment with this drug: RLW, CENL. Contributed to the final manuscript revisions and compiled all figures for this manuscript, completed all statistical analyses and contributed to final manuscript revisions: RLW. Conceived the study, participated in its design and coordination, and helped in manuscript revisions as well as supervised all experimental work: AHLANG. Conceived and designed the experiments: AHLANG. Performed the experiments: CENL AND RLW. Analyzed the data: AND. Contributed reagents/materials/analysis tools: AHLANG. Wrote the paper: CENL.