Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII) Activity and Sinoatrial Nodal Pacemaker Cell Energetics

Yael Yaniv; Harold A. Spurgeon; Bruce D. Ziman; Edward G. Lakatta

doi:10.1371/journal.pone.0057079

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Open Access

Peer-reviewed

Research Article

Ca²⁺/Calmodulin-Dependent Protein Kinase II (CaMKII) Activity and Sinoatrial Nodal Pacemaker Cell Energetics

Yael Yaniv,

Affiliation Laboratory of Cardiovascular Science, Gerontology Research Center, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America
⨯
Harold A. Spurgeon,

Affiliation Laboratory of Cardiovascular Science, Gerontology Research Center, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America
⨯
Bruce D. Ziman,

Affiliation Laboratory of Cardiovascular Science, Gerontology Research Center, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America
⨯
Edward G. Lakatta

* E-mail: LakattaE@mail.nih.gov

Affiliation Laboratory of Cardiovascular Science, Gerontology Research Center, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America
⨯

Ca²⁺/Calmodulin-Dependent Protein Kinase II (CaMKII) Activity and Sinoatrial Nodal Pacemaker Cell Energetics

Yael Yaniv,
Harold A. Spurgeon,
Bruce D. Ziman,
Edward G. Lakatta

Published: February 25, 2013
https://doi.org/10.1371/journal.pone.0057079

About the Authors

Yael Yaniv

Affiliation Laboratory of Cardiovascular Science, Gerontology Research Center, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America

Harold A. Spurgeon

Bruce D. Ziman

Edward G. Lakatta

* E-mail: LakattaE@mail.nih.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YY EGL. Performed the experiments: YY. Analyzed the data: YY. Contributed reagents/materials/analysis tools: HAS BDZ. Wrote the paper: YY EGL.

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Mitochondria
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Phosphorylation
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Rabbits
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Pacemakers
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Intracellular membranes
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Signal inhibition
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Adenylyl cyclase
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Curve fitting
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