About the Authors

Xin Chen

Affiliations Department of Molecular Carcinogenesis, The University of Texas M.D. Anderson Cancer Center, Science Park, Smithville, Texas, United States of America, Program in Molecular Carcinogenesis, Graduate School of Biomedical Sciences (GSBS), Houston, Texas, United States of America

Bigang Liu

Affiliation Department of Molecular Carcinogenesis, The University of Texas M.D. Anderson Cancer Center, Science Park, Smithville, Texas, United States of America

Qiuhui Li

Affiliations Department of Molecular Carcinogenesis, The University of Texas M.D. Anderson Cancer Center, Science Park, Smithville, Texas, United States of America, Center of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

Sofia Honorio

Affiliation Department of Molecular Carcinogenesis, The University of Texas M.D. Anderson Cancer Center, Science Park, Smithville, Texas, United States of America

Xin Liu

Affiliations Department of Molecular Carcinogenesis, The University of Texas M.D. Anderson Cancer Center, Science Park, Smithville, Texas, United States of America, Department of Nutritional Science, University of Texas at Austin, Austin, Texas, United States of America

Can Liu

Affiliations Department of Molecular Carcinogenesis, The University of Texas M.D. Anderson Cancer Center, Science Park, Smithville, Texas, United States of America, Program in Molecular Carcinogenesis, Graduate School of Biomedical Sciences (GSBS), Houston, Texas, United States of America

Asha S. Multani

Affiliation Department of Genetics, the University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America

Tammy Calhoun-Davis

Affiliation Department of Molecular Carcinogenesis, The University of Texas M.D. Anderson Cancer Center, Science Park, Smithville, Texas, United States of America

Dean G. Tang

dtang@mdanderson.org

Affiliations Department of Molecular Carcinogenesis, The University of Texas M.D. Anderson Cancer Center, Science Park, Smithville, Texas, United States of America, Program in Molecular Carcinogenesis, Graduate School of Biomedical Sciences (GSBS), Houston, Texas, United States of America, Centers for Cancer Epigenetics, Stem Cell and Developmental Biology, RNA Interference and Non-coding RNAs, and Molecular Carcinogenesis, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America, Cancer Stem Cell Institute, Research Center for Translational Medicine, East Hospital, Tongji University School of Medicine, Shanghai, China

Competing Interests

The corresponding author, Dr. Dean Tang, is currently an Academic Editor for PLOS ONE and that co-author Dr. Dean Tang is a PLOS ONE Editorial Board member. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: XC BGL QHL SH DGT. Performed the experiments: XC BGL QHL SH CL XL ASM TCD. Analyzed the data: XC QHL DGT. Wrote the paper: XC DGT.