About the Authors
- Hiroaki Asai
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Affiliation Department of Bioregulatory Medicine, Ehime University Graduate School of Medicine, Ehime, Japan
- Hiroshi Fujiwara
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* E-mail: yunarief@m.ehime-u.ac.jp (HF); yasukawa@m.ehime-u.ac.jp (MY)
Affiliations Department of Bioregulatory Medicine, Ehime University Graduate School of Medicine, Ehime, Japan, Department of Cell Growth and Tumor Regulation, Ehime University Proteo-Medicine Research Center, Ehime, Japan
- Jun An
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Affiliation Department of Bioregulatory Medicine, Ehime University Graduate School of Medicine, Ehime, Japan
- Toshiki Ochi
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Affiliations Department of Bioregulatory Medicine, Ehime University Graduate School of Medicine, Ehime, Japan, Princess Margaret Hospital, Ontario Cancer Institute, Ontario, Canada
- Yukihiro Miyazaki
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Affiliation Department of Bioregulatory Medicine, Ehime University Graduate School of Medicine, Ehime, Japan
- Kozo Nagai
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Affiliation Department of Pediatrics, Ehime University Graduate School of Medicine, Ehime, Japan
- Sachiko Okamoto
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Affiliation Center for Cell and Gene Therapy, Takara Bio Inc., Shiga, Japan
- Junichi Mineno
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Affiliation Center for Cell and Gene Therapy, Takara Bio Inc., Shiga, Japan
- Kiyotaka Kuzushima
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Affiliation Division of Immunology, Aichi Cancer Center, Aichi, Japan
- Hiroshi Shiku
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Affiliation Department of Cancer Vaccine and Immuno-Gene Therapy, Mie University Graduate School of Medicine, Mie, Japan
- Hirofumi Inoue
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Affiliation Department of Biochemistry and Molecular Genetics, Ehime University Graduate School of Medicine, Ehime, Japan
- Masaki Yasukawa
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* E-mail: yunarief@m.ehime-u.ac.jp (HF); yasukawa@m.ehime-u.ac.jp (MY)
Affiliations Department of Bioregulatory Medicine, Ehime University Graduate School of Medicine, Ehime, Japan, Department of Cell Growth and Tumor Regulation, Ehime University Proteo-Medicine Research Center, Ehime, Japan
Competing Interests
The authors except SO, JM and HS have declared that no competing interest exist. SO and JM are employee of Takara Bio, Inc.. HS is provided with research funding from Takara Bio, Inc.. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: HF MY. Performed the experiments: HA HF JA TO YM KN. Analyzed the data: HA HF HS MY. Contributed reagents/materials/analysis tools: SO JM KK HI. Wrote the paper: HA HF MY.