About the Authors
- Keiji Ozeki
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Affiliation Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan
- Satoshi Tanida
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* E-mail: stanida@med.nagoya-cu.ac.jp (ST); shigeki@m.ehime-u.ac.jp (SH)
Affiliation Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan
- Chie Morimoto
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Affiliation Department of Living Science Nutrition Course, Matsuyama Shinonome Junior College, Matsuyama, Ehime, Japan
- Yoshimasa Inoue
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Affiliation Carna Biosciences Incorporation, Kobe, Japan
- Tsutomu Mizoshita
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Affiliation Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan
- Hironobu Tsukamoto
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Affiliation Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan
- Takaya Shimura
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Affiliation Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan
- Hiromi Kataoka
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Affiliation Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan
- Takeshi Kamiya
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Affiliation Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan
- Eiji Nishiwaki
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Affiliation Carna Biosciences Incorporation, Kobe, Japan
- Hiroshi Ishiguro
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Affiliation Department of Medical Technology School of Health Sciences, Gifu University of Medical Science, Seki, Gifu, Japan
- Shigeki Higashiyama
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* E-mail: stanida@med.nagoya-cu.ac.jp (ST); shigeki@m.ehime-u.ac.jp (SH)
Affiliations Department of Cell Growth and Tumor Regulation, Proteo-Medicine Research Center, Ehime University, Toon, Ehime, Japan, Department of Biochemistry and Molecular Genetics, Ehime University Graduate School of Medicine, Ehime University, Toon, Ehime, Japan
- Takashi Joh
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Affiliation Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan
Competing Interests
The authors have the following Competing interest: Yoshimasa Inoue and Eiji Nishiwaki are employed by commercial company Carna Biosciences Incorporation. There are no further patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors. All the authors declare that no financial conflict of interest exists in relation to the content of the article.
Author Contributions
Critical revision of the manuscript for important intellectual content: TJ SH. Statistical analysis: KO. Study supervision: ST TJ SH. Conceived and designed the experiments: ST TJ SH KO. Performed the experiments: KO CM. Analyzed the data: ST TJ SH TM HT TS HK TK KO. Contributed reagents/materials/analysis tools: YI EN HI SH. Wrote the paper: KO ST.