The 380 kb pCMU01 Plasmid Encodes Chloromethane Utilization Genes and Redundant Genes for Vitamin B12- and Tetrahydrofolate-Dependent Chloromethane Metabolism in Methylobacterium extorquens CM4: A Proteomic and Bioinformatics Study

Sandro Roselli; Thierry Nadalig; Stéphane Vuilleumier; Françoise Bringel

doi:10.1371/journal.pone.0056598

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Peer-reviewed

Research Article

The 380 kb pCMU01 Plasmid Encodes Chloromethane Utilization Genes and Redundant Genes for Vitamin B₁₂- and Tetrahydrofolate-Dependent Chloromethane Metabolism in Methylobacterium extorquens CM4: A Proteomic and Bioinformatics Study

Sandro Roselli,

Affiliation Département Génétique Moléculaire, Génomique, Microbiologie, Université de Strasbourg, UMR7156, Centre national de la recherche scientifique, Strasbourg, France
⨯
Thierry Nadalig,

Affiliation Département Génétique Moléculaire, Génomique, Microbiologie, Université de Strasbourg, UMR7156, Centre national de la recherche scientifique, Strasbourg, France
⨯
Stéphane Vuilleumier,

Affiliation Département Génétique Moléculaire, Génomique, Microbiologie, Université de Strasbourg, UMR7156, Centre national de la recherche scientifique, Strasbourg, France
⨯
Françoise Bringel

* E-mail: francoise.bringel@unistra.fr

Affiliation Département Génétique Moléculaire, Génomique, Microbiologie, Université de Strasbourg, UMR7156, Centre national de la recherche scientifique, Strasbourg, France
⨯

The 380 kb pCMU01 Plasmid Encodes Chloromethane Utilization Genes and Redundant Genes for Vitamin B₁₂- and Tetrahydrofolate-Dependent Chloromethane Metabolism in Methylobacterium extorquens CM4: A Proteomic and Bioinformatics Study

Sandro Roselli,
Thierry Nadalig,
Stéphane Vuilleumier,
Françoise Bringel

Published: April 9, 2013
https://doi.org/10.1371/journal.pone.0056598

About the Authors

Sandro Roselli

Affiliation Département Génétique Moléculaire, Génomique, Microbiologie, Université de Strasbourg, UMR7156, Centre national de la recherche scientifique, Strasbourg, France

Thierry Nadalig

Affiliation Département Génétique Moléculaire, Génomique, Microbiologie, Université de Strasbourg, UMR7156, Centre national de la recherche scientifique, Strasbourg, France

Stéphane Vuilleumier

Affiliation Département Génétique Moléculaire, Génomique, Microbiologie, Université de Strasbourg, UMR7156, Centre national de la recherche scientifique, Strasbourg, France

Françoise Bringel

* E-mail: francoise.bringel@unistra.fr

Affiliation Département Génétique Moléculaire, Génomique, Microbiologie, Université de Strasbourg, UMR7156, Centre national de la recherche scientifique, Strasbourg, France

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: FB SV. Performed the experiments: SR TN. Analyzed the data: SR FB. Contributed reagents/materials/analysis tools: TN SV FB. Wrote the paper: SR FB SV.

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Biosynthesis
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Cobalamins
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Genomics
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Protein metabolism
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Biochemical cofactors
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Cobalt
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Enzyme metabolism
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Outer membrane proteins
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