About the Authors

Solange Moll

Affiliation Institute of Clinical Pathology, University Hospital Geneva, Geneva, Switzerland

Martin Ebeling

Affiliation Non-clinical Safety, F. Hoffmann-La Roche Ltd, Basel, Switzerland

Franziska Weibel

Affiliation CV & Metabolic DTA Department, F. Hoffmann-La Roche Ltd, Basel, Switzerland

Annarita Farina

Affiliation Bioinformatics and Structural Biology Dept., Geneva University, Geneva, Switzerland

Andrea Araujo Del Rosario

Affiliation CV & Metabolic DTA Department, F. Hoffmann-La Roche Ltd, Basel, Switzerland

Jean Christophe Hoflack

Affiliation Non-clinical Safety, F. Hoffmann-La Roche Ltd, Basel, Switzerland

Silvia Pomposiello

Affiliation Non-clinical Safety, F. Hoffmann-La Roche Ltd, Basel, Switzerland

Marco Prunotto

marco.prunotto@roche.com

Affiliation Non-clinical Safety, F. Hoffmann-La Roche Ltd, Basel, Switzerland

Competing Interests

The authors have read the journal's policy and have the following conflicts: M.E, F.W, A.A.D.R., S.P., J.C.H and M.P are employees and shareholders of Hoffmann-La Roche Ltd., and S.M; and A.F. have no conflict of interest. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Critically revised the manuscript: ME AF SP. Conceived and designed the experiments: SM MP. Performed the experiments: ME FW AADR JCH. Analyzed the data: JCH. Wrote the paper: SM MP.