About the Authors

Mia D. Champion

Mia.Champion@asu.edu

Current address: Health Science Research, Biomedical Statistics and Informatics, Mayo Clinic, Scottsdale, Arizona, United States of America

Affiliation Center for Evolutionary Medicine & Informatics, Biodesign Institute, Arizona State University, Arizona, United States of America

Vanessa Gray

Contributed equally to this work with: Vanessa Gray, Carl Eberhard

Current address: Genome Sciences, University of Washington, Seattle, Washington, United States of America

Affiliation Center for Evolutionary Medicine & Informatics, Biodesign Institute, Arizona State University, Arizona, United States of America

Carl Eberhard

Contributed equally to this work with: Vanessa Gray, Carl Eberhard

Current address: The Galaxy Project, Atlanta, Georgia, United States of America

Affiliation Division of Pathogen Genomics, Translational Genomics Research Institute, Arizona, United States of America

Sudhir Kumar

Affiliation Center for Evolutionary Medicine & Informatics, Biodesign Institute, Arizona State University, Arizona, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MDC SK. Performed the experiments: MDC. Piloted customized PolyPhen prediction experiments: VG CE. Analyzed the data: MDC SK. Wrote the paper: MDC SK.