About the Authors

Aakrosh Ratan

Contributed equally to this work with: Aakrosh Ratan, Stephan C. Schuster

Affiliation Center for Comparative Genomics and Bioinformatics, Pennsylvania State University, University Park, Pennsylvania, United States of America

Webb Miller

Affiliation Center for Comparative Genomics and Bioinformatics, Pennsylvania State University, University Park, Pennsylvania, United States of America

Joseph Guillory

Affiliation Department of Molecular Biology, Genentech Inc., South San Francisco, California, United States of America

Jeremy Stinson

Affiliation Department of Molecular Biology, Genentech Inc., South San Francisco, California, United States of America

Somasekar Seshagiri

Affiliation Department of Molecular Biology, Genentech Inc., South San Francisco, California, United States of America

Stephan C. Schuster

Contributed equally to this work with: Aakrosh Ratan, Stephan C. Schuster

scs@bx.psu.edu

Affiliation Center for Comparative Genomics and Bioinformatics, Pennsylvania State University, University Park, Pennsylvania, United States of America

Competing Interests

Some of the authors are employed by a commercial company, Genentech Inc. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: AR WM SS SCS. Performed the experiments: JG JS. Analyzed the data: AR WM SS SCS. Contributed reagents/materials/analysis tools: AR SCS. Wrote the paper: AR SS SCS.