About the Authors

Meiye Wu

Affiliations Department of Biotechnology and Bioengineering, Sandia National Laboratory, Livermore, California, United States of America, Biochemistry and Molecular Biology Graduate Group, University of California Davis, Davis, California, United States of America

Matthew Piccini

Affiliation Department of Biotechnology and Bioengineering, Sandia National Laboratory, Livermore, California, United States of America

Chung-Yan Koh

Affiliation Department of Biotechnology and Bioengineering, Sandia National Laboratory, Livermore, California, United States of America

Kit S. Lam

Affiliations Biochemistry and Molecular Biology Graduate Group, University of California Davis, Davis, California, United States of America, Department of Hematology and Oncology, University of California Davis Medical Center, Sacramento, California, United States of America

Anup K. Singh

aksingh@sandia.gov

Affiliation Department of Biotechnology and Bioengineering, Sandia National Laboratory, Livermore, California, United States of America

Competing Interests

The authors have read the journal’s policy and have the following conflicts: Meiye Wu, Matthew Piccini, Chung-yan Koh, and Anup K. Singh are employees of Sandia National Laboratory. Sandia is a multiprogram laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the United States Department of Energy’s National Nuclear Security Administration under contract DE-AC04-94AL85000. Meiye Wu was also a graduate student at UC Davis, under Kit Lam, and financially supported by Sandia’s Special Degree program. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: MW KSL AKS. Performed the experiments: MW MP CK. Analyzed the data: MW AKS. Contributed reagents/materials/analysis tools: CK KSL AKS. Wrote the paper: MW.