About the Authors

Lan Guo

Contributed equally to this work with: Lan Guo, Heng Du

Affiliation Department of Pharmacology & Toxicology and Higuchi Bioscience Center, School of Pharmacy, University of Kansas, Lawrence, Kansas, United States of America

Heng Du

Contributed equally to this work with: Lan Guo, Heng Du

Affiliation Department of Pharmacology & Toxicology and Higuchi Bioscience Center, School of Pharmacy, University of Kansas, Lawrence, Kansas, United States of America

Shiqiang Yan

Affiliations Department of Pharmacology & Toxicology and Higuchi Bioscience Center, School of Pharmacy, University of Kansas, Lawrence, Kansas, United States of America, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu, People’s Republic of China

Xiaoping Wu

Affiliation Department of Neurosurgery, Physicians & Surgeons College of Columbia University, New York, New York, United States of America

Guy M. McKhann

Affiliation Department of Neurosurgery, Physicians & Surgeons College of Columbia University, New York, New York, United States of America

John Xi Chen

Affiliation Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

Shirley ShiDu Yan

shidu@ku.edu

Affiliation Department of Pharmacology & Toxicology and Higuchi Bioscience Center, School of Pharmacy, University of Kansas, Lawrence, Kansas, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SSY JXC LG HD. Performed the experiments: LG HD SQY XPW. Analyzed the data: LG HD SQY XPW. Contributed reagents/materials/analysis tools: LG HD SQY XPW GMM. Wrote the paper: SSY LG HD.