The Scaffolding Protein SYD-2/Liprin-α Regulates the Mobility and Polarized Distribution of Dense-Core Vesicles in C. elegans Motor Neurons

Patricia R. Goodwin; Peter Juo

doi:10.1371/journal.pone.0054763

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Open Access

Peer-reviewed

Research Article

The Scaffolding Protein SYD-2/Liprin-α Regulates the Mobility and Polarized Distribution of Dense-Core Vesicles in C. elegans Motor Neurons

Patricia R. Goodwin,

Affiliations Department of Molecular Physiology and Pharmacology, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, Massachusetts, United States of America, Graduate Program in Neuroscience, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, Massachusetts, United States of America
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Peter Juo

* E-mail: peter.juo@tufts.edu

Affiliation Department of Molecular Physiology and Pharmacology, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, Massachusetts, United States of America
⨯

The Scaffolding Protein SYD-2/Liprin-α Regulates the Mobility and Polarized Distribution of Dense-Core Vesicles in C. elegans Motor Neurons

Patricia R. Goodwin,
Peter Juo

Published: January 24, 2013
https://doi.org/10.1371/journal.pone.0054763

About the Authors

Patricia R. Goodwin

Affiliations Department of Molecular Physiology and Pharmacology, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, Massachusetts, United States of America, Graduate Program in Neuroscience, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, Massachusetts, United States of America

Peter Juo

* E-mail: peter.juo@tufts.edu

Affiliation Department of Molecular Physiology and Pharmacology, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PRG PJ. Performed the experiments: PRG. Analyzed the data: PRG PJ. Contributed reagents/materials/analysis tools: PRG PJ. Wrote the paper: PRG PJ.

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Neuronal dendrites
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Axons
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Motor neurons
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Neuropeptides
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Fluorescence imaging
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Caenorhabditis elegans
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Neurons
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Synapses
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