About the Authors

Fatiha Kateb

Affiliations Institute of Structural Biology, Helmholtz Zentrum München, Neuherberg, Germany, Biomolecular NMR and Center for Integrated Protein Science Munich at Department Chemie, Technische Universität München, Garching, Germany

Helene Perrin

Affiliation Institut National de la Santé Et de la Recherche Médicale U590, Centre Léon Bérard, Université Claude Bernard Lyon I, Lyon, France

Konstantinos Tripsianes

Affiliations Institute of Structural Biology, Helmholtz Zentrum München, Neuherberg, Germany, Biomolecular NMR and Center for Integrated Protein Science Munich at Department Chemie, Technische Universität München, Garching, Germany

Peijian Zou

Affiliations Institute of Structural Biology, Helmholtz Zentrum München, Neuherberg, Germany, Biomolecular NMR and Center for Integrated Protein Science Munich at Department Chemie, Technische Universität München, Garching, Germany, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China

Roberta Spadaccini

Affiliation Dipartimento di Chimica, Università degli Studi di Napoli “Federico II”, Napoli, Italy

Matthew Bottomley

Affiliation Novartis Vaccines and Diagnostics, Siena, Italy

Titus M. Franzmann

Affiliation Biomolecular NMR and Center for Integrated Protein Science Munich at Department Chemie, Technische Universität München, Garching, Germany

Johannes Buchner

Affiliation Biomolecular NMR and Center for Integrated Protein Science Munich at Department Chemie, Technische Universität München, Garching, Germany

Stephane Ansieau

Affiliation Institut National de la Santé Et de la Recherche Médicale U590, Centre Léon Bérard, Université Claude Bernard Lyon I, Lyon, France

Michael Sattler

sattler@helmholtz-muenchen.de

Affiliations Institute of Structural Biology, Helmholtz Zentrum München, Neuherberg, Germany, Biomolecular NMR and Center for Integrated Protein Science Munich at Department Chemie, Technische Universität München, Garching, Germany, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China

Competing Interests

M.J. Bottomley is currently an employee of Novartis Vaccines & Diagnostics. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: FK SA MS. Performed the experiments: FK HP KT PZ RS MB TMF. Analyzed the data: FK HP TMF SA MS. Contributed reagents/materials/analysis tools: JB. Wrote the paper: FK SA MS.