About the Authors

James W. Wells

j.wells3@uq.edu.au

Affiliation Center for Advanced Orthopaedic Studies, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America

Christopher H. Evans

Affiliation Center for Advanced Orthopaedic Studies, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America

Milcah C. Scott

Affiliation Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, United States of America

Barbara C. Rütgen

Affiliation Central Laboratory, Department of Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria

Timothy D. O'Brien

Affiliation Veterinary Population Medicine Department and Stem Cell Institute, University of Minnesota, Saint Paul, Minnesota, United States of America

Jaime F. Modiano

Affiliation Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, United States of America

Goran Cvetkovic

Affiliation Kyon AG, Zurich, Switzerland

Slobodan Tepic

Affiliation Kyon AG, Zurich, Switzerland

Competing Interests

The authors declare that Goran Cvetkovic and Slobodan Tepic have an affiliation with Kyon AG; Goran Cvetkovic is an employee and Slobodan Tepic is the CEO and President. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JWW CHE ST. Performed the experiments: JWW GC. Analyzed the data: JWW. Contributed reagents/materials/analysis tools: MCS BCR TDO JFM. Wrote the paper: JWW CHE JFM ST.