About the Authors

Joseph M. D. Rastrick

Affiliation Respiratory Pharmacology, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom

Christopher S. Stevenson

Affiliations Respiratory Pharmacology, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom, Roche, Nutley, New Jersey, United States of America

Suffwan Eltom

Affiliation Respiratory Pharmacology, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom

Megan Grace

Affiliation Respiratory Pharmacology, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom

Meirion Davies

Affiliation Respiratory Pharmacology, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom

Iain Kilty

Affiliation Pfizer, Pfizer Inc, Cambridge, Massachusetts, United States of America

Steven M. Evans

Affiliation Pfizer, Pfizer Inc, Cambridge, Massachusetts, United States of America

Manolis Pasparakis

Affiliation University of Cologne, Cologne, Germany

Matthew C. Catley

Affiliation AstraZeneca, Molndal, Sweden, United Kingdom

Toby Lawrence

Affiliation Centre d'Immunologie Marseille-Luminy, Marseille, France

Ian M. Adcock

Affiliation Airway Disease, Imperial College London, United Kingdom

Maria G. Belvisi

m.belvisi@imperial.ac.uk

Affiliation Respiratory Pharmacology, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom

Mark A. Birrell

Affiliation Respiratory Pharmacology, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom

Competing Interests

The authors declare that during the time when this work was performed CSS worked for Roche, IK and SE worked for Pfizer and MCC worked for AstraZeneca. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JMDR CSS MGB MAB. Performed the experiments: JMDR SE MAB. Analyzed the data: JMDR MG MD IMA MGB MAB. Contributed reagents/materials/analysis tools: IK SME MP MCC TL. Wrote the paper: JMDR MGB MAB.