Activation of Thromboxane A2 Receptor (TP) Increases the Expression of Monocyte Chemoattractant Protein -1 (MCP-1)/Chemokine (C-C motif) Ligand 2 (CCL2) and Recruits Macrophages to Promote Invasion of Lung Cancer Cells

Xiuling Li; Hsin-Hsiung Tai

doi:10.1371/journal.pone.0054073

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Open Access

Peer-reviewed

Research Article

Activation of Thromboxane A₂ Receptor (TP) Increases the Expression of Monocyte Chemoattractant Protein -1 (MCP-1)/Chemokine (C-C motif) Ligand 2 (CCL2) and Recruits Macrophages to Promote Invasion of Lung Cancer Cells

Xiuling Li,

Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky, United States of America
⨯
Hsin-Hsiung Tai

* E-mail: htai1@email.uky.edu

Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky, United States of America
⨯

Activation of Thromboxane A₂ Receptor (TP) Increases the Expression of Monocyte Chemoattractant Protein -1 (MCP-1)/Chemokine (C-C motif) Ligand 2 (CCL2) and Recruits Macrophages to Promote Invasion of Lung Cancer Cells

Xiuling Li,
Hsin-Hsiung Tai

Published: January 17, 2013
https://doi.org/10.1371/journal.pone.0054073

About the Authors

Xiuling Li

Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky, United States of America

Hsin-Hsiung Tai

* E-mail: htai1@email.uky.edu

Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: XL HHT. Performed the experiments: XL. Analyzed the data: XL HHT. Contributed reagents/materials/analysis tools: HHT. Wrote the paper: XL HHT.

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Macrophages
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Non-small cell lung cancer
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Prostate cancer
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Breast cancer
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Lung and intrathoracic tumors
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Renal cancer
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Gene expression
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Metastasis
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