About the Authors

Lin Huang

Contributed equally to this work with: Lin Huang, Zhen-Bo Wang

Affiliations State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China, Graduate School, Chinese Academy of Sciences, Beijing, China

Zhen-Bo Wang

Contributed equally to this work with: Lin Huang, Zhen-Bo Wang

Affiliation State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China

Zong-Zhe Jiang

Affiliations State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China, Graduate School, Chinese Academy of Sciences, Beijing, China

Meng-Wen Hu

Affiliations State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China, Graduate School, Chinese Academy of Sciences, Beijing, China

Fei Lin

Affiliation State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China

Qing-Hua Zhang

Affiliation State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China

Yi-Bo Luo

Affiliation State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China

Yi Hou

Affiliation State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China

Yong Zhao

Affiliation State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China

Heng-Yu Fan

Affiliation Life Science Institute, Zhejiang University, Zhejiang Province, China

Heide Schatten

Affiliation Department of Veterinary Pathobiology, University of Missouri, Columbia, Missouri, United States of America

Qing-Yuan Sun

sunqy@ioz.ac.cn

Affiliation State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Contributed the Tsc1 flox/flox mice: YZ. Contributed the cyp19-cre mice: HYF. Read and modified the manuscript: HS. Conceived and designed the experiments: LH ZBW QYS. Performed the experiments: LH ZBW ZZJ MWH QHZ FL YBL. Analyzed the data: LH. Contributed reagents/materials/analysis tools: YH. Wrote the paper: QYS.