About the Authors

Ketan S. Gajiwala

Ketan.gajiwala@pfizer.com

Affiliation Cancer Structural Biology within Oncology Medicinal Chemistry, Pfizer Worldwide Research and Development, San Diego, California, United States of America

Karen Maegley

Affiliation Oncology Research Unit, Pfizer Worldwide Research and Development, San Diego, California, United States of America

RoseAnn Ferre

Affiliation Cancer Structural Biology within Oncology Medicinal Chemistry, Pfizer Worldwide Research and Development, San Diego, California, United States of America

You-Ai He

Affiliation Cancer Structural Biology within Oncology Medicinal Chemistry, Pfizer Worldwide Research and Development, San Diego, California, United States of America

Xiu Yu

Affiliation Cancer Structural Biology within Oncology Medicinal Chemistry, Pfizer Worldwide Research and Development, San Diego, California, United States of America

Competing Interests

All authors are employees of Pfizer, Inc. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: KSG. Performed the experiments: KSG KM RF YH XY. Analyzed the data: KSG KM. Contributed reagents/materials/analysis tools: KSG KM RF YH XY. Wrote the paper: KSG KM.