About the Authors

Raafat P. Fares

Contributed equally to this work with: Raafat P. Fares, Amor Belmeguenai, Pascal E. Sanchez

Affiliations Université de Lyon, Lyon, France, Université Lyon 1, Villeurbanne, France, Inserm, Institut National de la Santé et de la Recherche Médicale, U1028, Lyon Neuroscience Research Center, Tiger Team, Lyon, France, CNRS, Centre National de la Recherche Scientifique, UMR5292, Lyon Neuroscience Research Center, Tiger Team, Lyon, France, IDÉE, Institut Des ÉpilepsiEs, Lyon, France, IRBA, Institut de Recherche Biomédicale des Armées, Brétigny-sur-Orge, France

Amor Belmeguenai

Contributed equally to this work with: Raafat P. Fares, Amor Belmeguenai, Pascal E. Sanchez

Affiliations Université de Lyon, Lyon, France, Université Lyon 1, Villeurbanne, France, Inserm, Institut National de la Santé et de la Recherche Médicale, U1028, Lyon Neuroscience Research Center, Tiger Team, Lyon, France, CNRS, Centre National de la Recherche Scientifique, UMR5292, Lyon Neuroscience Research Center, Tiger Team, Lyon, France, IDÉE, Institut Des ÉpilepsiEs, Lyon, France

Pascal E. Sanchez

Contributed equally to this work with: Raafat P. Fares, Amor Belmeguenai, Pascal E. Sanchez

Affiliations Université de Lyon, Lyon, France, Université Lyon 1, Villeurbanne, France, Inserm, Institut National de la Santé et de la Recherche Médicale, U1028, Lyon Neuroscience Research Center, Tiger Team, Lyon, France, CNRS, Centre National de la Recherche Scientifique, UMR5292, Lyon Neuroscience Research Center, Tiger Team, Lyon, France, IDÉE, Institut Des ÉpilepsiEs, Lyon, France

Hayet Y. Kouchi

Affiliations Université de Lyon, Lyon, France, Université Lyon 1, Villeurbanne, France, Inserm, Institut National de la Santé et de la Recherche Médicale, U1028, Lyon Neuroscience Research Center, Tiger Team, Lyon, France, CNRS, Centre National de la Recherche Scientifique, UMR5292, Lyon Neuroscience Research Center, Tiger Team, Lyon, France, IDÉE, Institut Des ÉpilepsiEs, Lyon, France

Jacques Bodennec

Affiliations Université de Lyon, Lyon, France, Université Lyon 1, Villeurbanne, France, Inserm, Institut National de la Santé et de la Recherche Médicale, U1028, Lyon Neuroscience Research Center, Tiger Team, Lyon, France, CNRS, Centre National de la Recherche Scientifique, UMR5292, Lyon Neuroscience Research Center, Tiger Team, Lyon, France, IDÉE, Institut Des ÉpilepsiEs, Lyon, France

Anne Morales

Affiliations Université de Lyon, Lyon, France, Université Lyon 1, Villeurbanne, France, Inserm, Institut National de la Santé et de la Recherche Médicale, U1028, Lyon Neuroscience Research Center, Tiger Team, Lyon, France, CNRS, Centre National de la Recherche Scientifique, UMR5292, Lyon Neuroscience Research Center, Tiger Team, Lyon, France, IDÉE, Institut Des ÉpilepsiEs, Lyon, France

Béatrice Georges

Affiliations Université de Lyon, Lyon, France, Université Lyon 1, Villeurbanne, France, Inserm, Institut National de la Santé et de la Recherche Médicale, U1028, Lyon Neuroscience Research Center, Tiger Team, Lyon, France, CNRS, Centre National de la Recherche Scientifique, UMR5292, Lyon Neuroscience Research Center, Tiger Team, Lyon, France, IDÉE, Institut Des ÉpilepsiEs, Lyon, France

Chantal Bonnet

Affiliations Université de Lyon, Lyon, France, Université Lyon 1, Villeurbanne, France, Inserm, Institut National de la Santé et de la Recherche Médicale, U1028, Lyon Neuroscience Research Center, Tiger Team, Lyon, France, CNRS, Centre National de la Recherche Scientifique, UMR5292, Lyon Neuroscience Research Center, Tiger Team, Lyon, France, IDÉE, Institut Des ÉpilepsiEs, Lyon, France

Sandrine Bouvard

Affiliations Université de Lyon, Lyon, France, Université Lyon 1, Villeurbanne, France, Inserm, Institut National de la Santé et de la Recherche Médicale, U1028, Lyon Neuroscience Research Center, Tiger Team, Lyon, France, CNRS, Centre National de la Recherche Scientifique, UMR5292, Lyon Neuroscience Research Center, Tiger Team, Lyon, France, IDÉE, Institut Des ÉpilepsiEs, Lyon, France

Robert S. Sloviter

Affiliation Department of Neurobiology, Pharmacology and Toxicology, Morehouse School of Medicine, Atlanta, Georgia, United States of America

Laurent Bezin

laurent.bezin@univ-lyon1.fr

Affiliations Université de Lyon, Lyon, France, Université Lyon 1, Villeurbanne, France, Inserm, Institut National de la Santé et de la Recherche Médicale, U1028, Lyon Neuroscience Research Center, Tiger Team, Lyon, France, CNRS, Centre National de la Recherche Scientifique, UMR5292, Lyon Neuroscience Research Center, Tiger Team, Lyon, France, IDÉE, Institut Des ÉpilepsiEs, Lyon, France

Competing Interests

R. P. Fares, M. Le Cavorsin and L. Bezin invented, designed and patented the prototype of the Marlau™ cage, which is now further developed and sold by the company Viewpoint, which has no connection or financial link with the authors’ laboratory. There are no further patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: AB LB PES RPF. Performed the experiments: AB BG CB HYK JB PES RPF SB. Analyzed the data: AB AM HYK JB LB PES RPF. Wrote the paper: AB LB PES RPF RSS.