About the Authors

Fabian Zimmer

Affiliation Computer Assisted Clinical Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany

Frank G. Zöllner

frank.zoellner@medma.uni-heidelberg.de

Affiliation Computer Assisted Clinical Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany

Simone Hoeger

Affiliation Department of Medicine V, University Medical Centre Mannheim, Heidelberg University, Mannheim, Germany

Sarah Klotz

Affiliation Department of Medicine V, University Medical Centre Mannheim, Heidelberg University, Mannheim, Germany

Charalambos Tsagogiorgas

Affiliation Clinic for Anaesthesiology and Intensive Care, University Medical Centre Mannheim, Heidelberg University, Mannheim, Germany

Bernhard K. Krämer

Affiliation Department of Medicine V, University Medical Centre Mannheim, Heidelberg University, Mannheim, Germany

Lothar R. Schad

Affiliation Computer Assisted Clinical Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany

Competing Interests

This study was in part sponsored by “Bayer HealthCare”. The Chair in Computer Assisted Clinical Medicine has a master research agreement with Siemens. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: FGZ FZ SH SK CT BK LS. Performed the experiments: FGZ FZ SH SK CT. Analyzed the data: FGZ FZ SH SK. Contributed reagents/materials/analysis tools: FGZ FZ SH SK CT. Wrote the paper: FGZ FZ SK.