About the Authors

Huan Cai

Affiliation Metabolism Unit, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America

Hongyu Chen

Affiliation Receptor Pharmacology Unit, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America

Tie Yi

Affiliation Metabolism Unit, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America

Caitlin M. Daimon

Affiliation Metabolism Unit, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America

John P. Boyle

Affiliation Institute for Cardiovascular Research, Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, West Yorkshire, United Kingdom

Chris Peers

Affiliation Institute for Cardiovascular Research, Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, West Yorkshire, United Kingdom

Stuart Maudsley

Contributed equally to this work with: Stuart Maudsley, Bronwen Martin

Affiliation Receptor Pharmacology Unit, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America

Bronwen Martin

Contributed equally to this work with: Stuart Maudsley, Bronwen Martin

martinbro@mail.nih.gov

Affiliation Metabolism Unit, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SM BM. Performed the experiments: H. Chen TY H. Cai JPB CMD. Analyzed the data: SM BM JPB H.Chen. Contributed reagents/materials/analysis tools: SM BM CP. Wrote the paper: SM BM CMD H. Chen H. Cai.