About the Authors

Matthias Scheffler

Contributed equally to this work with: Matthias Scheffler, Thomas Zander

Affiliations Department I for Internal Medicine, University Hospital of Cologne, Cologne, Germany, Center for Integrated Oncology Köln Bonn, Cologne, Germany

Thomas Zander

Contributed equally to this work with: Matthias Scheffler, Thomas Zander

Affiliations Department I for Internal Medicine, University Hospital of Cologne, Cologne, Germany, Center for Integrated Oncology Köln Bonn, Cologne, Germany

Lucia Nogova

Affiliations Department I for Internal Medicine, University Hospital of Cologne, Cologne, Germany, Center for Integrated Oncology Köln Bonn, Cologne, Germany

Carsten Kobe

Affiliation Clinic for Nuclear Medicine, University Hospital of Cologne, Cologne, Germany

Deniz Kahraman

Affiliation Clinic for Nuclear Medicine, University Hospital of Cologne, Cologne, Germany

Markus Dietlein

Affiliation Clinic for Nuclear Medicine, University Hospital of Cologne, Cologne, Germany

Irini Papachristou

Affiliations Department I for Internal Medicine, University Hospital of Cologne, Cologne, Germany, Center for Integrated Oncology Köln Bonn, Cologne, Germany

Lukas Heukamp

Affiliations Center for Integrated Oncology Köln Bonn, Cologne, Germany, Institute of Pathology, University Hospital Cologne, Cologne, Germany

Reinhard Büttner

Affiliations Center for Integrated Oncology Köln Bonn, Cologne, Germany, Institute of Pathology, University Hospital Cologne, Cologne, Germany

Ron Boellaard

Affiliation Department of Nuclear Medicine and PET Research, VU University Medical Center Amsterdam, Amsterdam, The Netherlands

Adriaan A. Lammertsma

Affiliation Department of Nuclear Medicine and PET Research, VU University Medical Center Amsterdam, Amsterdam, The Netherlands

Silvia Querings

Affiliation Max-Planck Institute for Neurological Research, Cologne, Germany

Erich Stoelben

Affiliation Lung Clinic Merheim, Hospital of Cologne, Cologne, Germany

Walburga Engel-Riedel

Affiliation Lung Clinic Merheim, Hospital of Cologne, Cologne, Germany

Bernd Neumaier

Affiliation Max-Planck Institute for Neurological Research, Cologne, Germany

Jürgen Wolf

juergen.wolf@uk-koeln.de

Affiliations Department I for Internal Medicine, University Hospital of Cologne, Cologne, Germany, Center for Integrated Oncology Köln Bonn, Cologne, Germany

Competing Interests

During the termination phase of the trial, we have received research fundings from Roche, a commercial source. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MS TZ LN MD JW. Performed the experiments: MS TZ LN CK DK IP LH R. Büttner SQ BN JW. Analyzed the data: MS TZ. Contributed reagents/materials/analysis tools: MS TZ CK DK IP R. Boellaard AAL LH R. Büttner BN ES WER JW. Wrote the paper: MS TZ LN CK DK MD IP LH R. Boellaard R. Büttner AAL SQ ES WER BN JW.