About the Authors
- Juan Martin Caballero
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Contributed equally to this work with: Juan Martin Caballero, Ana Garzón
Affiliation Laboratory Animal Unit, Barcelona Biomedical Research Park, Barcelona, Spain
- Ana Garzón
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Contributed equally to this work with: Juan Martin Caballero, Ana Garzón
Current address: Azurebio S.L., Madrid, Spain
Affiliation Cancer Vaccines Unit, R & D Department, Chimera Pharma S.L.U., Madrid, Spain
- Leticia González-Cintado
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Affiliation Department of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Madrid, Spain
- Wioleta Kowalczyk
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Current address: CSIRO Materials Science and Engineering, Australia
Affiliation Department of Experimental and Health Sciences, Pompeu Fabra University, Barcelona Biomedical Research Park, Barcelona, Spain
- Ignacio Jimenez Torres
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Current address: Igenbiotech, Madrid, Spain
Affiliation Cancer Vaccines Unit, R & D Department, Chimera Pharma S.L.U., Madrid, Spain
- Gloria Calderita
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Current address: Nimgenetics, Parque Científico de Madrid, Madrid, Spain
Affiliation Cancer Vaccines Unit, R & D Department, Chimera Pharma S.L.U., Madrid, Spain
- Margarita Rodriguez
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Current address: Hospital Universitario Sanchinarro, Madrid, Spain
Affiliation Cancer Vaccines Unit, R & D Department, Chimera Pharma S.L.U., Madrid, Spain
- Virgínia Gondar
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Current address: Hospital Universitario de la Princesa, Unidad de Biología Molecular, Instituto Investigación Sanitaria Princesa, Madrid, Spain
Affiliation Cancer Vaccines Unit, R & D Department, Chimera Pharma S.L.U., Madrid, Spain
- Juan Jose Bernal
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Current address: Protein Alternatives S.L., Tres Cantos, Madrid, Spain
Affiliation Cancer Vaccines Unit, R & D Department, Chimera Pharma S.L.U., Madrid, Spain
- Carlos Ardavín
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Affiliation Department of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Madrid, Spain
- David Andreu
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Affiliation Department of Experimental and Health Sciences, Pompeu Fabra University, Barcelona Biomedical Research Park, Barcelona, Spain
- Thomas Zürcher
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Current address: ForMune S.L., Vivero de Innovación, Navarra, Spain
Affiliation Cancer Vaccines Unit, R & D Department, Chimera Pharma S.L.U., Madrid, Spain
- Cayetano von Kobbe
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* E-mail: cvonkobbe@cbm.uam.es
Current address: Molecular Biology Centre “Severo Ochoa”, Spanish Research Council (CBMSO-CSIC), Universidad Autónoma de Madrid, Madrid, Spain
Affiliation Cancer Vaccines Unit, R & D Department, Chimera Pharma S.L.U., Madrid, Spain
Competing Interests
AG, IJT, GC, MR, VG, JJB, TZ and CvK were employed by Chimera Pharma S.L.U. during the course of this project. Currently Chimera Pharma is under judicial liquidation after a meeting of creditorś period of time. None of the authors belongs to Chimera anymore. The VLP-E7 and VLP-E7-B constructs described in this paper are now propietary of VLP The Vaccineś Company S.L. (VLP Bio) and protected under PCT WO 2011/054996. The new owners of the intellectual property rights agree with the publication of these data. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: CvK TZ JMC CA. Performed the experiments: JMC AG LGC GC MR VG. Analyzed the data: JMC AG CvK TZ DA CA. Contributed reagents/materials/analysis tools: JJB DA IJT WK. Wrote the paper: CvK.