About the Authors

Yunhui Du

Affiliations Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, China, Department of Marine Bioengineering, Marine College, Shandong University, Weihai, Shandong, China

Li Yan

Affiliation Department of Physiology and Pathophysiology, Institute of Basic Medical Sciences, Peking Union Medical College, Beijing, China

Jin Wang

Affiliation Department of Physiology, Shanxi Medical University, Taiyuan, Shanxi, China

Wenzhang Zhan

Affiliation Department of Internal Medicine, General Hospital of Tonghua Mining Group CO. LTD, Baishan, Jilin, China

Kai Song

Affiliation Department of Internal Medicine, A Peace Hospital Attached to Changzhi Medical College, Changzhi, Shanxi, China

Xue Han

Affiliation Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, China

Xiao Li

Affiliation Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, China

Jimin Cao

Affiliation Department of Physiology and Pathophysiology, Institute of Basic Medical Sciences, Peking Union Medical College, Beijing, China

Huirong Liu

liuhr2000@126.com

Affiliations Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, China, The Key Laboratory of Remodeling-related Cardiovascular Diseases, Capital Medical University, Ministry of Education, Beijing, China

Competing Interests

One of the authors (Wenzhang Zhan) is employed by the commerical company General Hospital of Tonghua Mining Group CO. LTD. There are no patents, products in development or marketed products to declare. However, this affiliation does not alter the author’s adherence to all the PLOS ONE policies on sharing data and materials. The other authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YD HL. Performed the experiments: YD LY JW HX LX. Analyzed the data: YD LY XL. Contributed reagents/materials/analysis tools: WZ JC KS. Wrote the paper: YD HL.