About the Authors
- Areej Abuhammad
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Affiliations Department of Pharmacology, University of Oxford, Oxford, United Kingdom, Faculty of Pharmacy, University of Jordan, Amman, Jordan, Department of Biochemistry, University of Oxford, Oxford, United Kingdom
- Elizabeth Fullam
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Current address: School of Biosciences, University of Birmingham, Birmingham, United Kingdom
Affiliations Department of Pharmacology, University of Oxford, Oxford, United Kingdom, Department of Chemistry, University of Oxford, Oxford, United Kingdom
- Edward D. Lowe
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Affiliation Department of Biochemistry, University of Oxford, Oxford, United Kingdom
- David Staunton
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Affiliation Department of Biochemistry, University of Oxford, Oxford, United Kingdom
- Akane Kawamura
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Affiliations Department of Pharmacology, University of Oxford, Oxford, United Kingdom, Department of Chemistry, University of Oxford, Oxford, United Kingdom
- Isaac M. Westwood
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Current address: Divisions of Structural Biology and Cancer Therapeutics, Institute of Cancer Research, London, United Kingdom
Affiliations Department of Pharmacology, University of Oxford, Oxford, United Kingdom, Department of Chemistry, University of Oxford, Oxford, United Kingdom
- Sanjib Bhakta
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Current address: Department of Biological Science, University of London, London, United Kingdom
Affiliation Department of Pharmacology, University of Oxford, Oxford, United Kingdom
- Alun Christopher Garner
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Current address: School of Science and Technology, Nottingham Trent University, Nottingham, United Kingdom
Affiliation Department of Chemistry, University of Oxford, Oxford, United Kingdom
- David L. Wilson
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Affiliation Department of Chemistry, University of Oxford, Oxford, United Kingdom
- Peter T. Seden
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Affiliation Department of Chemistry, University of Oxford, Oxford, United Kingdom
- Stephen G. Davies
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Affiliation Department of Chemistry, University of Oxford, Oxford, United Kingdom
- Angela J. Russell
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Affiliations Department of Pharmacology, University of Oxford, Oxford, United Kingdom, Department of Chemistry, University of Oxford, Oxford, United Kingdom
- Elspeth F. Garman
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Affiliation Department of Biochemistry, University of Oxford, Oxford, United Kingdom
- Edith Sim
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* E-mail: E.Sim@kingston.ac.uk
Affiliations Department of Pharmacology, University of Oxford, Oxford, United Kingdom, Faculty of Science, Engineering and Computing Kingston University, Kingston, United Kingdom
Competing Interests
The authors have the following interests. E.S. and S.B. are members of the MRC UK TB Drug Discovery consortium, TBD-UK (http://www.tbd-uk.org.uk/). This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.
Author Contributions
Conceived and designed the experiments: AA ES EF SB. Performed the experiments: AA EF DS AK IMW SB ACG DLW PTS. Analyzed the data: AA ES AJR SB EDL EFG. Contributed reagents/materials/analysis tools: SGD AJR. Wrote the paper: AA ES EFG.