About the Authors

Jonathan S. Wall

jwall@utmck.edu

Affiliations Department of Medicine, University of Tennessee Graduate School of Medicine, Knoxville, Tennessee, United States of America, Department of Radiology, University of Tennessee Graduate School of Medicine, Knoxville, Tennessee, United States of America

Stephen J. Kennel

Affiliations Department of Medicine, University of Tennessee Graduate School of Medicine, Knoxville, Tennessee, United States of America, Department of Radiology, University of Tennessee Graduate School of Medicine, Knoxville, Tennessee, United States of America

Angela Williams

Affiliation Department of Medicine, University of Tennessee Graduate School of Medicine, Knoxville, Tennessee, United States of America

Tina Richey

Affiliation Department of Medicine, University of Tennessee Graduate School of Medicine, Knoxville, Tennessee, United States of America

Alan Stuckey

Affiliation Department of Radiology, University of Tennessee Graduate School of Medicine, Knoxville, Tennessee, United States of America

Ying Huang

Affiliation Department of Medicine, University of Tennessee Graduate School of Medicine, Knoxville, Tennessee, United States of America

Sallie Macy

Affiliation Department of Medicine, University of Tennessee Graduate School of Medicine, Knoxville, Tennessee, United States of America

Robert Donnell

Affiliation Department of Biomedical and Diagnostic Sciences, University of Tennessee College of Veterinary Medicine, Knoxville, Tennessee, United States of America

Robin Barbour

Affiliation Neotope Biosciences, South San Francisco, California, United States of America

Peter Seubert

Affiliation Neotope Biosciences, South San Francisco, California, United States of America

Dale Schenk

Affiliation Neotope Biosciences, South San Francisco, California, United States of America

Competing Interests

RB, PS, and DS are employees of Neotope Biosciences/Elan. JSW and SJK receive royalties from a patent associated with the 2A4 mAb (US patent #7,928,203). This work was supported by a collaborative research grant from Elan Pharmaceuticals, South San Francisco, USA; however, this does not alter the authors' adherence to PLOS ONE policies including data sharing and materials.

Author Contributions

Conceived and designed the experiments: JSW SJK RB PS. Performed the experiments: SJK TR AS AW YH RD SM. Analyzed the data: JSW SJK PS DS. Wrote the paper: JSW SJK RB PS DS.