About the Authors

Fernando L. Martin

Contributed equally to this work with: Fernando L. Martin, S. Jeson Sangaralingham

Affiliation Cardiorenal Research Laboratory, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, United States of America

S. Jeson Sangaralingham

Contributed equally to this work with: Fernando L. Martin, S. Jeson Sangaralingham

sangaralingham.jeson@mayo.edu

Affiliation Cardiorenal Research Laboratory, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, United States of America

Brenda K. Huntley

Affiliation Cardiorenal Research Laboratory, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, United States of America

Paul M. McKie

Affiliation Cardiorenal Research Laboratory, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, United States of America

Tomoko Ichiki

Affiliation Cardiorenal Research Laboratory, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, United States of America

Horng H. Chen

Affiliation Cardiorenal Research Laboratory, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, United States of America

Josef Korinek

Affiliation Cardiorenal Research Laboratory, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, United States of America

Gerald E. Harders

Affiliation Cardiorenal Research Laboratory, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, United States of America

John C. Burnett Jr

Affiliation Cardiorenal Research Laboratory, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, United States of America

Competing Interests

The authors have read the journal's policy and have the following conflicts. Mayo Clinic has licensed CD-NP to Nile Therapeutics, Inc and Dr. Chen is a consultant to Nile Therapeutics. Dr. Burnett chairs the Scientific Advisory Board of Nile Therapeutics. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: FLM SJS HHC JCB. Performed the experiments: FLM SJS BKH GEH. Analyzed the data: FLM SJS BKH PMM TI JK JCB. Contributed reagents/materials/analysis tools: HHC JCB. Wrote the paper: FLM SJS BKH PMM TI HHC JK GEH JCB.