About the Authors
- Zi Di
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Affiliation Division of Toxicology, Leiden/Amsterdam Center for Drug Research, Leiden University, Leiden, The Netherlands
- Bram Herpers
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Affiliation Division of Toxicology, Leiden/Amsterdam Center for Drug Research, Leiden University, Leiden, The Netherlands
- Lisa Fredriksson
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Affiliation Division of Toxicology, Leiden/Amsterdam Center for Drug Research, Leiden University, Leiden, The Netherlands
- Kuan Yan
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Affiliation Imaging & BioInformatics, Leiden Institute of Advanced Computer Science, Leiden University, The Netherlands
- Bob van de Water
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Affiliation Division of Toxicology, Leiden/Amsterdam Center for Drug Research, Leiden University, Leiden, The Netherlands
- Fons J. Verbeek
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Affiliation Imaging & BioInformatics, Leiden Institute of Advanced Computer Science, Leiden University, The Netherlands
- John H. N. Meerman
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* E-mail: meerman@lacdr.leidenuniv.nl
Affiliation Division of Toxicology, Leiden/Amsterdam Center for Drug Research, Leiden University, Leiden, The Netherlands
Competing Interests
The authors have stated in the manuscript that our study was supported by TI Pharma, project D3-201. TI Pharma is an independent non-profit organization whose mission is to is to establish, support and manage public-private collaborations between academia and the (inter-)national pharmaceutical industry. None of the authors of the manuscript has received direct funding, is or has been employed by, is a consultant for a commercial organization that collaborates with TI Pharma in this project, or owns patents or has products in development or markets products related to the subject of the manuscript. Therefore, this funding by TI Pharma does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: ZD BH LF BW JHM. Performed the experiments: ZD BH LF. Analyzed the data: ZD BH KY FJV JHM. Contributed reagents/materials/analysis tools: KY FJV BH LF. Wrote the paper: ZD BH FJV BW JHM.