About the Authors

Zaozao Chen

Affiliations Department of Cell Biology and Physiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America, Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America, Program in Molecular and Cellular Biophysics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Elizabeth Lessey

Affiliation Department of Cell Biology and Physiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Matthew E. Berginski

Affiliation Department of Biomedical Engineering, University of North Carolina, Chapel Hill, North Carolina, United States of America

Li Cao

Affiliation Department of Biomedical Engineering, Duke University, Durham, North Carolina, United States of America

Jonathan Li

Affiliation Department of Biomedical Engineering, Duke University, Durham, North Carolina, United States of America

Xavier Trepat

Affiliation Institute for Bioengineering of Catalonia, University of Barcelona, and Ciber Enfermedades Respiratorias, Barcelona, Spain

Michelle Itano

Affiliations Department of Cell Biology and Physiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America, Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Shawn M. Gomez

Affiliations Department of Biomedical Engineering, University of North Carolina, Chapel Hill, North Carolina, United States of America, Department of Computer Science, University of North Carolina at Chapel Hill, Chapell Hill, North Carolina, United States of America, Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Maryna Kapustina

Affiliations Department of Cell Biology and Physiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America, Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Cai Huang

Affiliation Markey Cancer Center and Department of Molecular & Biomedical Pharmacology, University of Kentucky, Lexington, Kentucky, United States of America

Keith Burridge

Affiliations Department of Cell Biology and Physiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America, Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

George Truskey

Affiliation Department of Biomedical Engineering, Duke University, Durham, North Carolina, United States of America

Ken Jacobson

frap@med.unc.edu

Affiliations Department of Cell Biology and Physiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America, Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America, Program in Molecular and Cellular Biophysics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ZC SG MK CH KB GT KJ. Performed the experiments: ZC EL JL MI. Analyzed the data: ZC EL MB. Contributed reagents/materials/analysis tools: LC XT. Wrote the paper: ZC EL MB KJ.