About the Authors

Yuichi Tamura

u1@ta-mu.net

Affiliation Department of Cardiology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan

Yasuo Nakajima

Affiliation Development and Medical Affairs Division, GlaxoSmithKline KK, Shibuya-ku, Tokyo, Japan

Yasushi Ozeki

Affiliation Development and Medical Affairs Division, GlaxoSmithKline KK, Shibuya-ku, Tokyo, Japan

Tomohiko Ono

Affiliation Department of Cardiology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan

Makoto Takei

Affiliation Department of Cardiology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan

Tsunehisa Yamamoto

Affiliation Department of Cardiology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan

Keiichi Fukuda

Affiliation Department of Cardiology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan

Competing Interests

Yasuo Nakajima and Yasushi Ozeki are employees of the study sponsor, GlaxoSmithKline KK. The other authors have declared that no competing interests exist. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: YT KF. Performed the experiments: TY MT TO. Analyzed the data: YT YN. Contributed reagents/materials/analysis tools: YN YO. Wrote the paper: YT YN.