About the Authors

Bernhard M. Schuldt

Contributed equally to this work with: Bernhard M. Schuldt, Anke Guhr

Affiliation Graduiertenschule Aachen Institute for Advanced Study in Computational Engineering Science (AICES), RWTH Aachen, Aachen, Germany

Anke Guhr

Contributed equally to this work with: Bernhard M. Schuldt, Anke Guhr

Affiliation Robert Koch Institute, Berlin, Germany

Michael Lenz

Affiliation Graduiertenschule Aachen Institute for Advanced Study in Computational Engineering Science (AICES), RWTH Aachen, Aachen, Germany

Sabine Kobold

Affiliation Robert Koch Institute, Berlin, Germany

Ben D. MacArthur

Affiliations Centre for Human Development, Stem Cells and Regeneration, Institute of Developmental Sciences, University of Southampton, Southampton, United Kingdom, School of Mathematics, University of Southampton, Southampton, United Kingdom, Institute for Life Sciences, University of Southampton, United Kingdom

Andreas Schuppert

Affiliation Graduiertenschule Aachen Institute for Advanced Study in Computational Engineering Science (AICES), RWTH Aachen, Aachen, Germany

Peter Löser

fj.mueller@zip-kiel.de (F-JM); loeserp@rki.de (PL)

Affiliation Robert Koch Institute, Berlin, Germany

Franz-Josef Müller

fj.mueller@zip-kiel.de (F-JM); loeserp@rki.de (PL)

Affiliation Zentrum für Integrative Psychiatrie, Kiel, Germany

Competing Interests

The authors would like to formally state that the work leading to the manuscript has been funded in part by Bayer Technologies Services by providing salary to Bernhard Schuldt and Andreas Schuppert. Also, the work has been funded in part by a fellowship to Franz-Josef Müller by the Else Kröner Fresenius Stiftung. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials and there are no commercial or other interests (such as patents, products in development, consultancy etc.) tied to the manuscript. The funding sources had no influence on or took part in the interpretation of the scientific data presented or conclusions drawn.

Author Contributions

Conceived and designed the experiments: FJM PL. Performed the experiments: BMS ML. Analyzed the data: PL AG SK AS ML FJM BDM BMS. Wrote the paper: PL AG SK AS ML FJM BDM BMS.