About the Authors

Ruicheng Wei

Affiliation Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People’s Republic of China

Chunfu Yang

Affiliation Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People’s Republic of China

Mei Zeng

Affiliation Department of Infectious Diseases, Children's Hospital of Fudan University, Shanghai, People’s Republic of China

Frances Terry

Affiliation EpiVax, Inc., Providence, Rhode Island, United States of America

Kai Zhu

Affiliation Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People’s Republic of China

Chunhui Yang

Affiliation Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People’s Republic of China

Ralf Altmeyer

Affiliation Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People’s Republic of China

William Martin

Affiliation EpiVax, Inc., Providence, Rhode Island, United States of America

Anne S. De Groot

Affiliations EpiVax, Inc., Providence, Rhode Island, United States of America, Institute for Immunology and Informatics, University of Rhode Island, Providence, Rhode Island, United States of America

Qibin Leng

qbleng@sibs.ac.cn

Affiliation Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People’s Republic of China

Competing Interests

Anne S. De Groot, William Martin and Frances Terry are employees of EpiVax, Inc., a privately owned vaccine design company located in Providence, Rhode Island, Unoted States of America. These authors attest that this manuscript is free of bias related to their industry affiliations. Ryan Tassone of EpiVax assisted with editing this manuscript. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: QL ASD RA. Performed the experiments: RW CFY MZ FT KZ CHY WM. Analyzed the data: RW QL FT ASD. Wrote the paper: QL ASD RW.