About the Authors

Justin M. Scheer

scheer.justin@gene.com

Affiliation Department of Protein Chemistry, Genentech Inc., South San Francisco, California, United States of America

Wendy Sandoval

Affiliation Department of Protein Chemistry, Genentech Inc., South San Francisco, California, United States of America

J. Michael Elliott

Affiliation Department of Protein Chemistry, Genentech Inc., South San Francisco, California, United States of America

Lily Shao

Affiliation Department of Research Oncology, Genentech Inc., South San Francisco, California, United States of America

Elizabeth Luis

Affiliation Department of Protein Chemistry, Genentech Inc., South San Francisco, California, United States of America

Sock-Cheng Lewin-Koh

Affiliation Department of Biostatistics, Genentech Inc., South San Francisco, California, United States of America

Gabriele Schaefer

Affiliation Department of Research Oncology, Genentech Inc., South San Francisco, California, United States of America

Richard Vandlen

Affiliation Department of Protein Chemistry, Genentech Inc., South San Francisco, California, United States of America

Competing Interests

The authors have read the journal's policy and have the following conflicts: all authors are employees of Genentech. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JMS RV WS GS. Performed the experiments: WS JME JMS GS LS EL. Analyzed the data: WS JMS JME RV SCLK GS LS EL. Contributed reagents/materials/analysis tools: SCLK JME WS RV JMS LS. Wrote the paper: JMS WS GS RV.