About the Authors

Oxana Polyakova

Affiliation Platform Technology Sciences, GlaxoSmithKline, Stevenage, Hertfordshire, United Kingdom

Satty Borman

Affiliation Platform Technology Sciences, GlaxoSmithKline, Stevenage, Hertfordshire, United Kingdom

Rachel Grimley

Affiliation Platform Technology Sciences, GlaxoSmithKline, Stevenage, Hertfordshire, United Kingdom

Jessica Vamathevan

Affiliation Computational Biology, GlaxoSmithKline, Stevenage, Hertfordshire, United Kingdom

Brian Hayes

Affiliation Allergic Inflammation Discovery Performance Unit, GlaxoSmithKline, Stevenage, Hertfordshire, United Kingdom

Roberto Solari

roberto.2.solari@gsk.com

Affiliation Allergic Inflammation Discovery Performance Unit, GlaxoSmithKline, Stevenage, Hertfordshire, United Kingdom

Competing Interests

The authors have no consultancies on Sirtuins, have not filed patents on this Sirtuin 6 work, and have no Sirtuin 6 products in development or on the market. The authors confirm that the work and statements made in the paper are 100% motivated by putting scientific data in the public domain and do not seek to influence the authors’ or any third party’s potential position on the commercialisation of Sirtuin related products. The authors declare that they have no competing interests in Sirtuin 6. The authors’ employment status does not alter their adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: OP RG RS. Performed the experiments: OP BH SB. Analyzed the data: JV RS. Contributed reagents/materials/analysis tools: JV. Wrote the paper: RS OP RG.