About the Authors

Peiyan Wong

Affiliation Neuroscience and Behavioral Disorders Program, Duke-NUS Graduate Medical School Singapore, Singapore, Singapore

Cecilia Chin Roei Chang

Affiliation Neuroscience and Behavioral Disorders Program, Duke-NUS Graduate Medical School Singapore, Singapore, Singapore

Christine E. Marx

Affiliations Durham VA Medical Center, Department of Veterans Affairs, Durham, North Carolina, United States of America, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, United States of America

Marc G. Caron

Affiliations Department of Cell Biology, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Neurobiology, Duke University Medical Center, Durham, North Carolina, United States of America

William C. Wetsel

Affiliations Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Cell Biology, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Neurobiology, Duke University Medical Center, Durham, North Carolina, United States of America

Xiaodong Zhang

xiaodong.zhang@duke-nus.edu.sg

Affiliations Neuroscience and Behavioral Disorders Program, Duke-NUS Graduate Medical School Singapore, Singapore, Singapore, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Physiology, National University of Singapore, Singapore, Singapore

Competing Interests

The authors have the following interests: Dr. Marx is an applicant or co-applicant on pending patent applications on the use of neurosteroids in CNS disorders; no patents have been issued; no licensing is in place. Dr. Marx is an unpaid scientific advisor to Sage Therapeutics. There are no further patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: PW XDZ WCW MGC. Performed the experiments: PW CRCC. Analyzed the data: PW. Contributed reagents/materials/analysis tools: XDZ WCW MGC. Wrote the paper: PW CRCC CEM XDZ WCW MGC.