MHC Class II-Restricted Presentation of the Major House Dust Mite Allergen Der p 1 Is GILT-Dependent: Implications for Allergic Asthma

Laura Ciaccia West; Jeff E. Grotzke; Peter Cresswell

doi:10.1371/journal.pone.0051343

Loading metrics

Open Access

Peer-reviewed

Research Article

MHC Class II-Restricted Presentation of the Major House Dust Mite Allergen Der p 1 Is GILT-Dependent: Implications for Allergic Asthma

Laura Ciaccia West,

Affiliation Department of Immunobiology, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯
Jeff E. Grotzke,

Affiliation Department of Immunobiology, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯
Peter Cresswell

* E-mail: peter.cresswell@yale.edu

Affiliation Department of Immunobiology, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯

MHC Class II-Restricted Presentation of the Major House Dust Mite Allergen Der p 1 Is GILT-Dependent: Implications for Allergic Asthma

Laura Ciaccia West,
Jeff E. Grotzke,
Peter Cresswell

Published: January 11, 2013
https://doi.org/10.1371/journal.pone.0051343

About the Authors

Laura Ciaccia West

Affiliation Department of Immunobiology, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut, United States of America

Jeff E. Grotzke

Affiliation Department of Immunobiology, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut, United States of America

Peter Cresswell

* E-mail: peter.cresswell@yale.edu

Affiliation Department of Immunobiology, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LCW PC. Performed the experiments: LCW JEG. Analyzed the data: LCW JEG PC. Contributed reagents/materials/analysis tools: LCW JEG PC. Wrote the paper: LCW PC.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

T cells
Is the Subject Area "T cells" applicable to this article?

Thanks for your feedback.
Allergens
Is the Subject Area "Allergens" applicable to this article?

Thanks for your feedback.
Asthma
Is the Subject Area "Asthma" applicable to this article?

Thanks for your feedback.
Allergies
Is the Subject Area "Allergies" applicable to this article?

Thanks for your feedback.
Cysteine proteases
Is the Subject Area "Cysteine proteases" applicable to this article?

Thanks for your feedback.
Disulfide bonds
Is the Subject Area "Disulfide bonds" applicable to this article?

Thanks for your feedback.
Lymphocytes
Is the Subject Area "Lymphocytes" applicable to this article?

Thanks for your feedback.
Major histocompatibility complex
Is the Subject Area "Major histocompatibility complex" applicable to this article?

Thanks for your feedback.