About the Authors

Richa Batra

Affiliations Department of Bioinformatics and Functional Genomics, Institute of Pharmacy and Molecular Biotechnology, Bioquant, University of Heidelberg, Heidelberg, Germany, Division of Theoretical Bioinformatics, German Cancer Research Centre (DKFZ), Heidelberg, Germany

Nathalie Harder

Affiliations Department of Bioinformatics and Functional Genomics, Institute of Pharmacy and Molecular Biotechnology, Bioquant, University of Heidelberg, Heidelberg, Germany, Division of Theoretical Bioinformatics, German Cancer Research Centre (DKFZ), Heidelberg, Germany

Sina Gogolin

Affiliation Division of Tumor Genetics, German Cancer Research Centre (DKFZ), Heidelberg, Germany

Nicolle Diessl

Affiliation Department of Genomics and Proteomics Core Facility, High-Throughput Screening, German Cancer Research Center, Heidelberg, Germany

Zita Soons

Affiliations Department of Bioinformatics and Functional Genomics, Institute of Pharmacy and Molecular Biotechnology, Bioquant, University of Heidelberg, Heidelberg, Germany, Division of Theoretical Bioinformatics, German Cancer Research Centre (DKFZ), Heidelberg, Germany

Christina Jäger-Schmidt

Affiliation Division of Theoretical Bioinformatics, German Cancer Research Centre (DKFZ), Heidelberg, Germany

Christian Lawerenz

Affiliation Division of Theoretical Bioinformatics, German Cancer Research Centre (DKFZ), Heidelberg, Germany

Roland Eils

Affiliations Department of Bioinformatics and Functional Genomics, Institute of Pharmacy and Molecular Biotechnology, Bioquant, University of Heidelberg, Heidelberg, Germany, Division of Theoretical Bioinformatics, German Cancer Research Centre (DKFZ), Heidelberg, Germany

Karl Rohr

Affiliations Department of Bioinformatics and Functional Genomics, Institute of Pharmacy and Molecular Biotechnology, Bioquant, University of Heidelberg, Heidelberg, Germany, Division of Theoretical Bioinformatics, German Cancer Research Centre (DKFZ), Heidelberg, Germany

Frank Westermann

Affiliation Division of Tumor Genetics, German Cancer Research Centre (DKFZ), Heidelberg, Germany

Rainer König

r.koenig@dkfz.de

Affiliations Department of Bioinformatics and Functional Genomics, Institute of Pharmacy and Molecular Biotechnology, Bioquant, University of Heidelberg, Heidelberg, Germany, Division of Theoretical Bioinformatics, German Cancer Research Centre (DKFZ), Heidelberg, Germany

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RB RK FW. Performed the experiments: RB NH ND SG. Analyzed the data: RB NH. Contributed reagents/materials/analysis tools: RB NH FW RK KR CL CJS. Wrote the paper: RB RK. Conceived the study: RB RK. Carried out the analysis and drafted the manuscript: RB. Performed the image processing and tracking analysis: NH. Performed the experiments: ND. Performed the manual validation of the classifier: SG. Uploaded the images into the database ichip and maintained the database: CJS CL. Did stylist corrections of the manuscript: ZS. Guided the study: ZS RK FW KR RE. Proof-read the manuscript: RB NH SG ND ZS CJS CL RE KR FW RK.