Genome Context as a Predictive Tool for Identifying Regulatory Targets of the TetR Family Transcriptional Regulators

Sang Kyun Ahn; Leslie Cuthbertson; Justin R. Nodwell

doi:10.1371/journal.pone.0050562

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Open Access

Peer-reviewed

Research Article

Genome Context as a Predictive Tool for Identifying Regulatory Targets of the TetR Family Transcriptional Regulators

Sang Kyun Ahn,

Affiliations Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada, M. G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada
⨯
Leslie Cuthbertson,

Affiliations Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada, M. G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada
⨯
Justin R. Nodwell

* E-mail: nodwellj@mcmaster.ca

Affiliations Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada, M. G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada
⨯

Genome Context as a Predictive Tool for Identifying Regulatory Targets of the TetR Family Transcriptional Regulators

Sang Kyun Ahn,
Leslie Cuthbertson,
Justin R. Nodwell

Published: November 30, 2012
https://doi.org/10.1371/journal.pone.0050562

About the Authors

Sang Kyun Ahn

Affiliations Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada, M. G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada

Leslie Cuthbertson

Justin R. Nodwell

* E-mail: nodwellj@mcmaster.ca

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SKA LC JRN. Performed the experiments: SKA. Analyzed the data: SKA LC JRN. Contributed reagents/materials/analysis tools: SKA LC. Wrote the paper: SKA JRN.

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Gene regulation
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DNA
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Electrophoretic mobility shift assay
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Gene expression
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Transcriptional control
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Luminescence
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Streptomyces
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Enzyme regulation
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