About the Authors

Bin Bao

Affiliation Department of Pathology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America

Shadan Ali

Affiliation Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America

Aamir Ahmad

Affiliation Department of Pathology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America

Asfar S. Azmi

Affiliation Department of Pathology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America

Yiwei Li

Affiliation Department of Pathology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America

Sanjeev Banerjee

Affiliation Department of Pathology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America

Dejuan Kong

Affiliation Department of Pathology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America

Seema Sethi

Affiliation Department of Pathology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America

Amro Aboukameel

Affiliation Department of Pathology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America

Subhash B. Padhye

Affiliation ISTRA, Department of Chemistry, MCE Society's Abeda Inamdar Senior College of Arts, Science and Commerce, Pune, India

Fazlul H. Sarkar

fsarkar@med.wayne.edu

Affiliations Department of Pathology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America, Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America

Competing Interests

Co-author Dr. Sarkar is a PLOS ONE Editorial Board member. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Analyzed the data: YL. Wrote the paper: BB FS. Contributed in animal experiment: SB. Contributed pathological expertise: SS. Evaluated immunohistochemical staining: SS. Carried out the cell culture and molecular experiment studies: BB A. Ahmad A. Azmi SA DK. Performed in vivo experiments: A. Aboukameel. Collected data: A. Aboukameel. Assisted in performing in vitro experiments: A. Ahmad. Participated in drug design: SP. Provided the research funding: BB FS.