About the Authors

James D. Nicholson

Affiliation Department of Ophthalmology and Visual Sciences, University of Maryland-Baltimore School of Medicine, Baltimore, Maryland, United States of America

Adam C. Puche

Affiliation Department of Anatomy and Neurobiology, University of Maryland-Baltimore School of Medicine, Baltimore, Maryland, United States of America

Yan Guo

Affiliation Department of Ophthalmology and Visual Sciences, University of Maryland-Baltimore School of Medicine, Baltimore, Maryland, United States of America

Daniel Weinreich

Affiliation Department of Pharmacology, University of Maryland-Baltimore School of Medicine, Baltimore, Maryland, United States of America

Bernard J. Slater

Current address: Department of Neurobiology, University of Illinois at Urbana-Champaign, Urbana-Champaign, Illinois, United States of America

Affiliation Department of Ophthalmology and Visual Sciences, University of Maryland-Baltimore School of Medicine, Baltimore, Maryland, United States of America

Steven L. Bernstein

slbernst@umaryland.edu

Affiliations Department of Ophthalmology and Visual Sciences, University of Maryland-Baltimore School of Medicine, Baltimore, Maryland, United States of America, Department of Anatomy and Neurobiology, University of Maryland-Baltimore School of Medicine, Baltimore, Maryland, United States of America

Competing Interests

The use of PGJ2 for NAION has been granted US patent #8,106,096 to the University of Maryland-Baltimore. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SLB JDN ACP DW. Performed the experiments: JDN YG BJS SLB DW. Analyzed the data: SLB JDN DW BJS. Contributed reagents/materials/analysis tools: SLB DW. Wrote the paper: SLB JDN DW.