About the Authors

Grzegorz Bilo

Affiliation Department of Cardiology, San Luca Hospital, Istituto Auxologico Italiano, Milan, Italy

Miriam Revera

Affiliation Department of Cardiology, San Luca Hospital, Istituto Auxologico Italiano, Milan, Italy

Maurizio Bussotti

Affiliation Cardiologia Riabilitativa, Fondazione Salvatore Maugeri, IRCCS, Milan, Italy

Daniele Bonacina

Affiliation Department of Clinical Medicine and Prevention, University of Milano-Bicocca, Milan, Italy

Katarzyna Styczkiewicz

Affiliation I Department of Cardiology and Hypertension, Jagiellonian University Medical College, Krakow, Poland

Gianluca Caldara

Affiliation Department of Cardiology, San Luca Hospital, Istituto Auxologico Italiano, Milan, Italy

Alessia Giglio

Affiliation Department of Cardiology, San Luca Hospital, Istituto Auxologico Italiano, Milan, Italy

Andrea Faini

Affiliation Department of Cardiology, San Luca Hospital, Istituto Auxologico Italiano, Milan, Italy

Andrea Giuliano

Affiliations Department of Cardiology, San Luca Hospital, Istituto Auxologico Italiano, Milan, Italy, Department of Clinical Medicine and Prevention, University of Milano-Bicocca, Milan, Italy

Carolina Lombardi

Affiliation Department of Cardiology, San Luca Hospital, Istituto Auxologico Italiano, Milan, Italy

Kalina Kawecka-Jaszcz

Affiliation I Department of Cardiology and Hypertension, Jagiellonian University Medical College, Krakow, Poland

Giuseppe Mancia

Affiliation Department of Clinical Medicine and Prevention, University of Milano-Bicocca, Milan, Italy

Piergiuseppe Agostoni

piergiuseppe.agostoni@unimi.it

Affiliation Centro Cardiologico Monzino, IRCCS, and Department of Cardiovascular Sciences, University of Milan, Milan, Italy

Gianfranco Parati

Affiliations Department of Cardiology, San Luca Hospital, Istituto Auxologico Italiano, Milan, Italy, Department of Clinical Medicine and Prevention, University of Milano-Bicocca, Milan, Italy

Competing Interests

The authors have the following interests. Study B was supported with an unrestricted grant from Boehringer-Ingelheim Germany and Banca Intesa San Paolo, Milan, Italy. Sapio Life Italy s.r.l., GE Healthcare, and Intercure Ltd. supplied the devices necessary for this study free of charge. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: PA GB GP GM. Performed the experiments: MR MB DB KS GC AG AF AG CL KK. Analyzed the data: PA GB MR GC. Wrote the paper: PA GP BG.