Exploiting Genomic Knowledge in Optimising Molecular Breeding Programmes: Algorithms from Evolutionary Computing

Steve O'Hagan; Joshua Knowles; Douglas B. Kell

doi:10.1371/journal.pone.0048862

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Open Access

Peer-reviewed

Research Article

Exploiting Genomic Knowledge in Optimising Molecular Breeding Programmes: Algorithms from Evolutionary Computing

Steve O'Hagan,

Affiliations School of Chemistry, The University of Manchester, Manchester, United Kingdom, The Manchester Institute of Biotechnology, The University of Manchester, Manchester, United Kingdom
⨯
Joshua Knowles,

Affiliations The Manchester Institute of Biotechnology, The University of Manchester, Manchester, United Kingdom, School of Computer Science, The University of Manchester, Manchester, United Kingdom
⨯
Douglas B. Kell

* E-mail: dbk@manchester.ac.uk

Affiliations School of Chemistry, The University of Manchester, Manchester, United Kingdom, The Manchester Institute of Biotechnology, The University of Manchester, Manchester, United Kingdom
⨯

Exploiting Genomic Knowledge in Optimising Molecular Breeding Programmes: Algorithms from Evolutionary Computing

Steve O'Hagan,
Joshua Knowles,
Douglas B. Kell

Published: November 21, 2012
https://doi.org/10.1371/journal.pone.0048862

About the Authors

Steve O'Hagan

Affiliations School of Chemistry, The University of Manchester, Manchester, United Kingdom, The Manchester Institute of Biotechnology, The University of Manchester, Manchester, United Kingdom

Joshua Knowles

Affiliations The Manchester Institute of Biotechnology, The University of Manchester, Manchester, United Kingdom, School of Computer Science, The University of Manchester, Manchester, United Kingdom

Douglas B. Kell

* E-mail: dbk@manchester.ac.uk

Affiliations School of Chemistry, The University of Manchester, Manchester, United Kingdom, The Manchester Institute of Biotechnology, The University of Manchester, Manchester, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SOH JDK DBK. Performed the experiments: SOH JDK. Analyzed the data: SOH JDK DBK. Contributed reagents/materials/analysis tools: SOH JDK. Wrote the paper: SOH JDK DBK.

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Algorithms
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Entropy
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Evolutionary algorithms
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Natural selection
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Evolutionary genetics
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Fitness epistasis
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Genetic algorithms
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Species diversity
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