About the Authors

Lina Yin

Affiliations Pharmaceutical and Medicinal Chemistry, Saarland University & Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarbrücken, Germany, ElexoPharm GmbH, Saarbrücken, Germany

Qingzhong Hu

q.hu@mx.uni-saarland.de (QH); rolf.hartmann@helmholtz-hzi.de (RWH)

Affiliation Pharmaceutical and Medicinal Chemistry, Saarland University & Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarbrücken, Germany

Rolf W. Hartmann

q.hu@mx.uni-saarland.de (QH); rolf.hartmann@helmholtz-hzi.de (RWH)

Affiliation Pharmaceutical and Medicinal Chemistry, Saarland University & Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarbrücken, Germany

Competing Interests

The authors have declared that no competing interests exist. Although LY was employed by Elexopharm GmbH, this does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: LY QH. Performed the experiments: LY. Analyzed the data: LY QH. Contributed reagents/materials/analysis tools: LY QH. Wrote the paper: LY QH RWH.