About the Authors
- Masahiro Omoto
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Contributed equally to this work with: Masahiro Omoto, Satoru Yoshida
Affiliation Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan
- Satoru Yoshida
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Contributed equally to this work with: Masahiro Omoto, Satoru Yoshida
Affiliation Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan
- Hideyuki Miyashita
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Affiliation Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan
- Tetsuya Kawakita
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Affiliation Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan
- Kenji Yoshida
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Affiliation Genomic Science Laboratories, Dainippon Sumitomo Pharma Co., Ltd., Tokyo, Japan
- Akiyoshi Kishino
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Affiliation Genomic Science Laboratories, Dainippon Sumitomo Pharma Co., Ltd., Tokyo, Japan
- Toru Kimura
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Affiliation Genomic Science Laboratories, Dainippon Sumitomo Pharma Co., Ltd., Tokyo, Japan
- Shinsuke Shibata
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Affiliation Department of Physiology, Keio University School of Medicine, Tokyo, Japan
- Kazuo Tsubota
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Affiliation Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan
- Hideyuki Okano
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* E-mail: hidokano@a2.keio.jp (HO); shige@z8.keio.jp (SS)
Affiliation Department of Physiology, Keio University School of Medicine, Tokyo, Japan
- Shigeto Shimmura
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* E-mail: hidokano@a2.keio.jp (HO); shige@z8.keio.jp (SS)
Affiliation Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan
Competing Interests
The authors have read the journal's policy and have the following conflicts: MO, KT, HO and SS have applied for patent application on the use of Sema3A inhibitor for nerve regeneration [Application no. 2011-040128 (Japan)]. KY, AK, and TK are employees of Dainippon Sumitomo Pharma Co., Ltd. They have provided material for the study but were not involved in the study design or collection, analysis and interpretation of data. They were involved in the decision to submit the paper. These facts do not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: MO S. Shimmura KT HO. Performed the experiments: MO SY KY HM. Analyzed the data: MO SY HO HM T. Kawakita. Contributed reagents/materials/analysis tools: KY AK T. Kimura S. Shibata. Wrote the paper: S. Shimmura MO SY HO.