About the Authors

Jennifer Chow

Affiliation Department of Microbiology and Biotechnology, Biocenter Klein Flottbek, University of Hamburg, Hamburg, Germany

Filip Kovacic

Affiliation Institute of Molecular Enzyme Technology, Heinrich Heine University Duesseldorf, Research Center Juelich, Juelich, Germany

Yuliya Dall Antonia

Affiliation European Molecular Biology Laboratory (EMBL) Hamburg Outstation, c/o Deutsches Elektronen-Synchrotron (DESY), Hamburg, Germany

Ulrich Krauss

Affiliation Institute of Molecular Enzyme Technology, Heinrich Heine University Duesseldorf, Research Center Juelich, Juelich, Germany

Francesco Fersini

Affiliation European Molecular Biology Laboratory (EMBL) Hamburg Outstation, c/o Deutsches Elektronen-Synchrotron (DESY), Hamburg, Germany

Christel Schmeisser

Affiliation Department of Microbiology and Biotechnology, Biocenter Klein Flottbek, University of Hamburg, Hamburg, Germany

Benjamin Lauinger

Affiliation Institute of Bioorganic Chemistry, Heinrich Heine University Duesseldorf, Research Center Juelich, Juelich, Germany

Patrick Bongen

Affiliation Institute of Bioorganic Chemistry, Heinrich Heine University Duesseldorf, Research Center Juelich, Juelich, Germany

Joerg Pietruszka

Affiliation Institute of Bioorganic Chemistry, Heinrich Heine University Duesseldorf, Research Center Juelich, Juelich, Germany

Marlen Schmidt

Affiliation Department of Biotechnology & Enzyme Catalysis, Institute of Biochemistry, Greifswald University, Greifswald, Germany

Ina Menyes

Affiliation Department of Biotechnology & Enzyme Catalysis, Institute of Biochemistry, Greifswald University, Greifswald, Germany

Uwe T. Bornscheuer

Affiliation Department of Biotechnology & Enzyme Catalysis, Institute of Biochemistry, Greifswald University, Greifswald, Germany

Marrit Eckstein

Affiliation Bioprocess Development Consumer Specialties and Biocatalysis Biotechnology, Evonik Industries AG, Essen, Germany

Oliver Thum

Affiliation Bioprocess Development Consumer Specialties and Biocatalysis Biotechnology, Evonik Industries AG, Essen, Germany

Andreas Liese

Affiliation Institute of Technical Biocatalysis, Hamburg University of Technology, Hamburg, Germany

Jochen Mueller-Dieckmann

Affiliation European Molecular Biology Laboratory (EMBL) Hamburg Outstation, c/o Deutsches Elektronen-Synchrotron (DESY), Hamburg, Germany

Karl-Erich Jaeger

Affiliation Institute of Molecular Enzyme Technology, Heinrich Heine University Duesseldorf, Research Center Juelich, Juelich, Germany

Wolfgang R. Streit

wolfgang.streit@uni-hamburg.de

Affiliation Department of Microbiology and Biotechnology, Biocenter Klein Flottbek, University of Hamburg, Hamburg, Germany

Competing Interests

M. Eckstein and O. Thum are employed by Evonik Industries. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JC CS WRS. Performed the experiments: JC YDA FF BL PB MS IM. Analyzed the data: JC FK YDA UK FF BL PB MS IM UTB ME OT AL JMD KEJ WRS. Contributed reagents/materials/analysis tools: FK UK JP UTB ME OT AL JMD KEJ. Wrote the paper: JC WRS.