Common Genetic Variants in miR-1206 (8q24.2) and miR-612 (11q13.3) Affect Biogenesis of Mature miRNA Forms

Hye Kyung Kim; Ludmila Prokunina-Olsson; Stephen J. Chanock

doi:10.1371/journal.pone.0047454

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Open Access

Peer-reviewed

Research Article

Common Genetic Variants in miR-1206 (8q24.2) and miR-612 (11q13.3) Affect Biogenesis of Mature miRNA Forms

Hye Kyung Kim,

Affiliation Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America
⨯
Ludmila Prokunina-Olsson,

Affiliation Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America
⨯
Stephen J. Chanock

* E-mail: chanocks@mail.nih.gov

Affiliation Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America
⨯

Common Genetic Variants in miR-1206 (8q24.2) and miR-612 (11q13.3) Affect Biogenesis of Mature miRNA Forms

Hye Kyung Kim,
Ludmila Prokunina-Olsson,
Stephen J. Chanock

Published: October 15, 2012
https://doi.org/10.1371/journal.pone.0047454

About the Authors

Hye Kyung Kim

Affiliation Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America

Ludmila Prokunina-Olsson

Affiliation Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America

Stephen J. Chanock

* E-mail: chanocks@mail.nih.gov

Affiliation Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HKK LPO SJC. Performed the experiments: HKK. Analyzed the data: HKK LPO SJC. Wrote the paper: HKK LPO SJC.

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MicroRNAs
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Prostate cancer
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Colorectal cancer
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Breast cancer
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Genome-wide association studies
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Single nucleotide polymorphisms
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Genetic loci
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Transfection
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