About the Authors

Sarah L. Appleby

Contributed equally to this work with: Sarah L. Appleby, Michaelia P. Cockshell, Jyotsna B. Pippal

Affiliations Centre for Cancer Biology, South Australian Pathology, Adelaide, South Australia, Australia, Co-operative Research Centre for Biomarker Translation, La Trobe University, Melbourne, Victoria, Australia

Michaelia P. Cockshell

Contributed equally to this work with: Sarah L. Appleby, Michaelia P. Cockshell, Jyotsna B. Pippal

Affiliations Centre for Cancer Biology, South Australian Pathology, Adelaide, South Australia, Australia, Co-operative Research Centre for Biomarker Translation, La Trobe University, Melbourne, Victoria, Australia

Jyotsna B. Pippal

Contributed equally to this work with: Sarah L. Appleby, Michaelia P. Cockshell, Jyotsna B. Pippal

Affiliations Centre for Cancer Biology, South Australian Pathology, Adelaide, South Australia, Australia, Co-operative Research Centre for Biomarker Translation, La Trobe University, Melbourne, Victoria, Australia

Emma J. Thompson

Affiliations Centre for Cancer Biology, South Australian Pathology, Adelaide, South Australia, Australia, Co-operative Research Centre for Biomarker Translation, La Trobe University, Melbourne, Victoria, Australia

Jeffrey M. Barrett

Affiliations Centre for Cancer Biology, South Australian Pathology, Adelaide, South Australia, Australia, Co-operative Research Centre for Biomarker Translation, La Trobe University, Melbourne, Victoria, Australia

Katie Tooley

Affiliations Centre for Cancer Biology, South Australian Pathology, Adelaide, South Australia, Australia, Co-operative Research Centre for Biomarker Translation, La Trobe University, Melbourne, Victoria, Australia

Shaundeep Sen

Affiliation School of Medicine, University of Adelaide, Adelaide, Australia

Wai Yan Sun

Affiliations Centre for Cancer Biology, South Australian Pathology, Adelaide, South Australia, Australia, Co-operative Research Centre for Biomarker Translation, La Trobe University, Melbourne, Victoria, Australia, School of Medicine, University of Adelaide, Adelaide, Australia

Randall Grose

Affiliations Co-operative Research Centre for Biomarker Translation, La Trobe University, Melbourne, Victoria, Australia, Leukocyte Biology Laboratory, Women's and Children's Health Research Institute, Adelaide, South Australia, Australia

Ian Nicholson

Affiliations Co-operative Research Centre for Biomarker Translation, La Trobe University, Melbourne, Victoria, Australia, Leukocyte Biology Laboratory, Women's and Children's Health Research Institute, Adelaide, South Australia, Australia

Vitalina Levina

Affiliations Co-operative Research Centre for Biomarker Translation, La Trobe University, Melbourne, Victoria, Australia, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia

Ira Cooke

Affiliations Co-operative Research Centre for Biomarker Translation, La Trobe University, Melbourne, Victoria, Australia, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia

Gert Talbo

Affiliations Co-operative Research Centre for Biomarker Translation, La Trobe University, Melbourne, Victoria, Australia, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia

Angel F. Lopez

Affiliations Centre for Cancer Biology, South Australian Pathology, Adelaide, South Australia, Australia, Co-operative Research Centre for Biomarker Translation, La Trobe University, Melbourne, Victoria, Australia, School of Medicine, University of Adelaide, Adelaide, Australia

Claudine S. Bonder

claudine.bonder@health.sa.gov.au

Affiliations Centre for Cancer Biology, South Australian Pathology, Adelaide, South Australia, Australia, Co-operative Research Centre for Biomarker Translation, La Trobe University, Melbourne, Victoria, Australia, School of Medicine, University of Adelaide, Adelaide, Australia

Competing Interests

TransBio Limited is the management company of an Australian Government grant under the Co-operative Research Centre (CRC) Research funding program. SLA, JBP, MPC, EJT, KT, JMB, SS, WYS, RG, IN, VL, IC, GT, AFL and CSB have no commercial associations which might create a conflict of interest in connection with the submitted manuscript. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SLA GT AFL CSB. Performed the experiments: SLA MPC JBP EJT JMB KT SS WYS RG VL GT CSB. Analyzed the data: SLA JBP MPC EJT KT SS WYS GT CSB IN IC. Wrote the paper: SLA JBP MPC GT AFL CSB.